Olorin is an interactive filtering tool for next generation sequencing data coming from the study of large complex disease pedigrees.
In other words, Olorin is a Java-based application that integrates gene flow output from Merlin and next generation sequencing data.
Users can interactively filter and prioritize variants based on haplotype sharing across different sets of selected individuals and allele frequency in reference datasets.
Detailed instructions on how to use the Olorin utility on your Mac are available HERE.
Olorin is a cross-platform utility capable of running on any operating system that comes with Java support (e.g. Mac OS X, Windows, Linux).