CoLocalizer Express for Mac

5.5 MB   1,254 downloads
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A biomedical scientific app for quantification of colocalization in confocal fluorescence microscopy images

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CoLocalizer Express helps specialists define precise locations of proteins and nucleic acids in tissues or cells in order to let them analyze the functional significance of protein-protein interactions. CoLocalizer Express is used by leading research laboratories worldwide.

CoLocalizer Express application is compatible with images produced by all major brands of confocal fluorescence microscopes, including TIFF, Zeiss LSM 4 TIFF Chunky, Zeiss LSM 4 TIFF RGB Planar, JPEG, PICT, BMP, etc.

Quantification of colocalization using CoLocalizer Express is based on calculation of the following coefficients: Pearson's correlation coefficient (Rr), overlap coefficient according to Manders (R), overlap coefficients k1 and k2, colocalization coefficients m1 and m2, and colocalization coefficients M1 and M2.

Reliability of calculation is ensured by using the background correction tool. Using this tool, pixels with intensities potentially contributing to false counts are effectively removed from the image.

NOTE: To buy CoLocalizer Express via the App Store, an Apple account is required.
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Last updated on April 30th, 2015
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CoLocalizer Express - From CoLocalizer Express's main window you will be able to preview the pixel information and the scatter gram for the currently loaded image.CoLocalizer Express - The Background Correction window helps you select the image pattern from a predefined list.CoLocalizer Express - By accessing the ROI tab, you can select the ROI border color, enable or disable the ROI fill color and choose the ROI opacity.

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