Seurat is an easy to use, handy application that can be used to analyze sequences for somatic mutations and allelic imbalance.
Seurat tries to find these in paired tumor and normal genomes, as well as transcriptome data.
Being developed using the Java programming language, Seurat is a cross-platform utility that can be used on Mac OS X, Windows and Linux.
Here are some key features of "Seurat":
· Somatic mutation detection (SNVs, small indels)
· Structural variation detection on mate-paired data
· Allelic imbalance detection on RNA-seq data
· Somatic loss of heterozygosity detection
· Java 1.5 or later